Photo Induced DNA Cleavage

Introduction
Photo Induced DNA Cleavage is a property used in photodynamic therapy (PDT) for treatment of cancer. It is an emerging method of noninvasive treatment of cancer in which drugs like Photofrin show localized toxicity on photoactivation at the tumor cells leaving the healthy cells unaffected. The importance of PDT has necessitated a search for new photosensitizers that could show selective binding to DNA and photoactivation within the PDT window of 630-800 nm.

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